Impact of Myenteric Plexus Alterations on Diabetes Related Gastrointestinal Dysmotility

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Impact of Myenteric Plexus Alterations on Diabetes Related Gastrointestinal Dysmotility

CC This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. *Correspondence: Kyung Sik Park, MD Department of Internal Medicine, Dongsan Medical Cen...

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Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats

BACKGROUND/AIMS Type 1 diabetes is often accompanied by gastrointestinal motility disturbances. Vagal neuropathy, hyperglycemia, and alterations in the myenteric plexus have been proposed as underlying mechanism. We therefore studied the relationship between vagal function, gastrointestinal motiliy and characteristics of the enteric nervous system in the biobreeding (BB) rat known as model for ...

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Myenteric plexus in Hirschsprung's disease.

The absence of ganglion cells and the presence of abnormal bundles of unmyelinated fibres in the affected segment in Hirschsprung's disease was first well described by Whitehouse and Kernohan (f948). However, previous authors who have studied this problem have used standard transverse sections of the gut to demonstrate the abnormalities but these give a very inadequate view of the plexus which ...

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Neuropathic alterations of the myenteric plexus neurons following subacute intraperitoneal administration of salsolinol.

INTRODUCTION Impairment of the enteric nervous system has been suggested to occur within the pathogenesis of neurodegenerative diseases. Thus, in the current study, we consider salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, SAL) as a substance that can potentially induce myenteric neurodegen-eration. MATERIAL AND METHODS Male Wistar rats were subjected to continuous intrap...

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ژورنال

عنوان ژورنال: Journal of Neurogastroenterology and Motility

سال: 2013

ISSN: 2093-0879,2093-0887

DOI: 10.5056/jnm.2013.19.2.121